International Symposium on Modern Concepts in Endocarditis. Discover Barcelona'22.

Barcelona, 2022. 16th International Symposium

Saturday, 18 June

09:00-10:15

ISCVID Council

10:30-12:30

Duke Criteria for IE Working Group. 
D. Durack (USA), V. Fowler (USA) and J.M. Miro (Spain)

12:30-13:30

Pack Lunch 

13:30-14:00

Welcome Address

Dr. JM Campistol, Director Hospital Clinic of Barcelona
Dr. A. Trilla, Dean Faculty of Medicine, University of Barcelona
Dr. E. Quintana, Vicepresident of ISCVD Symposium
Dr. JM Miro, ISCVID President

14:00-16:00

Session I: Evolving epidemiology of infective endocarditis

Moderators: M. Martínez-Selles (Spain) and P. Moreillon (Switzerland)

14:00-14:20

IE trends and injection drug use. L.M. Baddour (USA) 

14:20-14:40

TAVI endocarditis: A new and growing clinical entity with surgical challenges. A. Regueiro (Spain)

14:40-15:00

The hidden face of IE: clinical characteristics and prognosis of IE in community centers. O. Gasch (Spain)

15:00-15:30

Discussion

15:30-15:45

Oral presentation-1

O-01

Infective endocarditis on MitraClip: a systematic literature review

L. Bertolino, F. Patauner, R. Gallo, M. Said Ramadan, E. Durante Mangoni.

Università degli studi della Campania “L. Vanvitelli”, AORN Ospedali dei Colli – Monaldi Hospital – Napoli, Italy.

15:45-16:00

Oral presentation-2

O-02

Staphylococcus aureusbacteremia, Cardiovascular implantable electronic device and the risk of CIED infection, endocarditis, pocket infection, and relapse.

C. Carlsen 1, A. Petropoulos 1, F. Gadler 2, M. Rasmussen 3, A. Berge 1.

1 Department of Infectious Diseases, Stockholm, Sweden;
Karolinska Institute, Stockholm, Sweden; 
Department of Infectious Diseases, Lund, Sweden.

16:00-16:30

Coffee & Poster Visit

16:30-18:30

Session II: Experimental and clinical pathogenesis

 Moderators: C. Garcia-de-la-Maria (Spain) and D. Durack (USA)

16:30-16:50

Impact of antibiotic treatment on the size of the vegetations in the animal model. A. Dahl (Denmark)

16:50-17:10

Novel phage lysins for treating staphylococcal endocardits: from bench to bedside. A. Bayer (USA)

17:10-17:30

Colonic neoplasms and S. gallolyticus and E. faecalis endocarditis. J.M. Pericas (Spain)

17:30-18:00

Discussion

18:00-18:15

Oral presentation-3

O-03

TARGETED PROTEOMIC ANALYSIS REVEALS ASSOCIATIONS BETWEEN SPECIFIC BACTERIAL VIRULENCE FACTORS AND SEVERITY IN STAPHYLOCOCCUS AUREUS BACTEREMIA.

C. Bouchiat 1, S. Bastien 1, I. Macavei 2, N. Mouton 2J.P. Rasigade 1 F. Vincent 1,  X. Duval 3, V. Le Moing 4, K. Moreau 1MJ. Lemoine 2, F. Vandenesch 1.

1 CIRI, Centre International de Recherche en Infectiologie, Université de Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France; Institut des Sciences Analytiques, UMR 5280, villeurbanne, France; University Hospital Bichat, paris, France. 4CHU de Montpellier, Montpellier, France

18:15-18:30

Oral presentation-4

O-04

Biofilms in endocarditis: is there a therapeutic consequence?
Put up for discussion

J. Kikhney1, A. Moter2

1Charité-Universitätsmedizin Berlin, Institute of Microbiology, Infectious Diseases and Immunology, MoKi Analytics, Berlin, Germany; 2Charité-Universitätsmedizin Berlin, Institute of Microbiology, Infectious Diseases and Immunology, Moter Diagnostics, MoKi Analytics, Berlin, Germany

18:30-19:30

Meet-to-party with a glass of wine/cava

20:00-22:00

Dinner for Speakers, chairs and ISCVID council members

Sunday, 19 June

8:30-10:30

Session III: Prevention of cardiovascular infections

 Moderators:  J.M. Tolosana (Spain) and J.T.M. van der Meer (Netherlands)

08:30-08:50

When will we have a clinical trial to clarify our doubts? B. Hoen (France)

08:50-09:10

Preventing infective endocarditis: How much does oral hygiene matter? P. Lockhart (USA)

09:10-09:30

Where are we now with antibiotic prevention of infective endocarditis? M.H. Thornhill (UK)

09:30-09:50

Is antimicrobial prophylaxis different for TAVI and CIED? Usefulness of antibacterial envelopes. A. Conen (Switzerland)

09:50-10:15

Discussion

10:15-10:30

Oral presentation-5

O-05

Efficacy and safety of mechanical thrombectomy in infective endocarditis-related large-vessel occlusion strokes: A systematic review of 87 cases.

P. Lapeña1, X. Urra1, J. Llopis1, G. Cuervo1, M. Hernández-Meneses1, O. Maisterra2, F. Escrihuela3, M.L. Pedro-Botet4, N. Benito5, C. Sáez6, C. Olmos7, F. Hernández-Fernández8, B. Vidal1, E. Sandoval1, C. Falces1, E. Quintana1, A. Moreno1, J.M. Miró1.

1Hospital Clínic de Barcelona, Barcelona, Spain; 2Hospital Universitari Vall d’Hebrón, Barcelona, Spain; 3Hospital Universitari de Bellvitge, L´Hospitalet de Llobregat, Spain; 4Hospital Universitari Germans Trias i Pujol, Badalona, Spain; 5Hospital de la Santa Creu i Sant Pau, Barcelona, Spain; 6Hospital Universitario de La Princesa, Madrid, Spain; 7Hospital Clínico San Carlos, Madrid, Spain; 8Complejo Hospitalario Universitario de Albacete, Albacete, Spain.

10:30-11:00

Coffee & Poster Visit

11:00-13:00

Session IV: Diagnosis of infective endocarditis

Moderators:  A. Perissinotti (Spain) and A.W. Karchmer (USA)

11:00-11:20

Improving microbiological diagnosis: molecular biology and cell-free DNA. C. Petti  (USA)

11:20-11:40

New imaging tools: MRI, PET/TC, leukocyte scintigraphy. M. Pizzi (Spain)

11:40-12:00

What is the current role of echo?  E.L. Fosbol (Denmark)

12:00-12:15

Discussion

12:15-13:00

ISCVID Initiative to update the Duke criteria

D. Durack (USA): Introduction

V. Fowler (USA), Chair, ISCVID task force: Report on progress

Feedback and suggestions from the audience moderated by D. Durack (USA) and V. Fowler (USA))

13:00-14:00

Pack Lunch 

14:00-16:00

Session V: How to improve the management of infective endocarditis

Moderators: J. Vila (Spain) and C. Selton-Suty (France)

14:00-14:20

How to develop and improve endocarditis teams?  V. Delgado (Netherlands)

14:20-14:40

Scores predicting endocarditis in Gram-Positive bacteremia, V. le Moing (France)

14:40-15:00

Scores, scores and more scores for cardiac surgey … Do they help us? B. Iung (France)

15:00-15:30

Discussion

15:30-15:45

Oral presentation-6

O-06

Efficacy The LAUsanne STAPHylococcus aureus ENdocarditis (LAUSTAPHEN) score: a prediction score to estimate initial patient risk for infective endocarditis in patients with S. aureus bacteremia.

M. Papadimitriou-Olivgeris, P. Monney, L. Mueller, L. Senn, B. Guery.

Lausanne University Hospital, Lausanne, Switzerland.

15:45-16:00

Oral presentation-7

O-07

Clinical and echocardiographic predictors of embolism in infective endocarditis. bacteremia.

M. Papadimitriou-Olivgeris, P. Monney, M. Kirsch, B. Guery.

Lausanne University Hospital, Lausanne, Switzerland.

16:00-16:30

Coffee & Poster Visit

16:30-18:30

Session VI: Challenging clinical cases (all lectures based on clinical cases with questions for the panel and audience)

Moderators: M. Hernández-Meneses (Spain) and E. Durante-Mangoni (Italy)

Discuss of the clinical cases: L. M. Baddour (USA), C. Fortes (Brazil), E. Sandoval (Spain), J. Ambrosioni (Spain) and G. Mestres (Spain)

16:30-16:54

Role of thrombectomy for ischemic stroke during IE. X. Urra (Spain)

16:54-17:18

Treating MDR Gram positive IE. P. Tattevin (France)

17:18-17:42

Management of prosthetic vascular graft infections. B. Hasse (Switzerland).

17:42-18:06

Fungal endocarditis. M. Hannan (Ireland)

18:06-18:30

CIED-associated IE. D.C. DeSimone (USA)

18:30-19:00

Special ISCVID lecture: the future of staphylococcal endocarditis. From biofilm eradication to artificial intelligence

Moderators: M. Pujol (Spain) and A. W. Karchmer (USA)
Speaker: V. Fowler (USA)

Monday, 20 June

8:00-10:00

Session VII: Advances in surgical management

Moderators: C. Mestres (Spain) and M. Borger (Germany)

8:00-8:20

Optimal timing for cardicac surgery after hemorragic stroke during IE. T. Toenst (Germany)

8:20-8:40

Challenging aspects of cardiac surgery: from valve repair to Commando procedure. E. Quintana (Spain)

8:40-9:00

Experience with percutaneus removal of right-sided vegetations (IDU, CIED). C. T. Starck (Germany)

9:00-9:30

Discussion

9:30-9:45

Oral presentation-8

O-08

Infective endocarditis and cardiovascular outcomes after transcatheter and surgical aortic valve replacement: a population-based cohort study.

P. Martin, K. Alexander, C. Anna.

Kantonsspital Aarau, Aarau, Switzerland.

9:45-10:00

Oral presentation-9

O-09

Postoperative fever after elective cardiac surgery: a retrospective study.

I. Zwartkruis, S. Keijmel, J. Jongenotter, G. Geuzebroek, I. Kouijzer.

Radboudumc, Nijmegen, Netherlands.

10:00-10:30

Coffee & Poster Visit

10:30-12:30

Session VIII: Changing the paradigm of antimicrobial treatment

Moderators: J.M. Miro (Spain) and V. Chu (USA)

10:30-10:50

Treat early, treat hard! Role of new bactericidal antibiotic combinations. E. Durante-Mangoni (Italy)

10:50-11:10

Switching to OPAT. New GAMES criteria and role of long-acting lipoglycopeptides. M. Kestler

11:10-12:15

Switching to oral therapy

11:10-11:30

Pros: Experience from Scandinavian countries. M. Rasmussen (Sweden)

11:30-11:50

Cons: What is being done outside the Scandinavian countries? E. Athan (Australia)

11:30-11:50

Feedback and suggestions from the audience moderated together with A.W. Karchmer (USA) and J.T.M. van der Meer (Netherlands)

9:45-10:00

Oral presentation-10

O-10

Long term suppressive antibiotic therapy in infective endocarditis: an observational study

 

A.L. Beaumont, F. Mestre, S. Decaux, C. Bertin, X. Duval, B. Iung, F. Rouzet, M. Para, N. Grall, M. Thy, L. Deconinck.

 

AP-HP, Paris, AP-HP, France

12:30-13:00

Final Session IX: Best papers on cardiovascular infections (2019-22). In memoriam J. Galvez (Spain)

Moderators: A. Moreno (Spain) and M. Hannan (Ireland)

Speaker: G. L. Cuervo (Spain)

13:00-13:30

Closing Ceremony and Awards Moderators: A. Moreno (Spain) and M. Hannan (Ireland)

Elias Abrutyn Award delivered by Dr A.W. Karchmer (3 min.introduction Dr. Abrutyn)

Ethan Rubinstein Award delivered by Dr D. Durack (3 min.introduction Dr. Rubinstein)

Dr. M. Rasmussen, President of the 2024 ISCVID Symposium, Malmö (Sweden)

Dr. E. Quintana ISCVID Symposium Vicepresident

Dr. JM Miro ISCVID President

13:30-14:30

Closing